Do not take APO-Ibuprofen 400 if you have an allergy to:
• Any medicine containing ibuprofen, aspirin or other NSAIDs
• Any of the ingredients listed at the end of this leaflet.

Many medicines used to treat headache, period pain and other aches and pains contain aspirin or NSAID medicines. If you are not sure if you are taking any of these medicines, ask your pharmacist.

DO NOT TAKE if you are allergic to aspirin or NSAID medicines or APO-Ibuprofen 400

Do not take APO-Ibuprofen 400 if you have:

• Asthma that is sensitive to aspirin or NSAIDs
• A peptic ulcer (i.e. stomach or duodenal ulcer), a recent history of one, or have had peptic ulcers before (especially if due to previous NSAID therapy)
• Recently (or have previously) vomited blood or material that looks like coffee grounds
• Recently (or previously) bled from the back passage (rectum), had black sticky bowel motions (stools) or bloody diarrhoea
• A condition resulting in an increased tendency to bleed
• Have a history of ulcerative colitis or Crohn's Disease
• Severe kidney disease
• Severe heart failure
• Severe liver disease
• Are being treated for pain following heart bypass surgery

Do not take APO-Ibuprofen 400 if you are pregnant or intend to become pregnant or during the first 6 months of pregnancy, except on doctor’s advice. Do not use at all in the last three months of pregnancy. It may affect your developing baby if you take it during pregnancy.

Do not take APO-Ibuprofen 400 after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If this medicine has expired or is damaged, return it to your pharmacist for disposal.

If you are not sure whether you should start taking APO-Ibuprofen 400, talk to your pharmacist or doctor.